Between-network connectivity occurs in brain regions lacking layer IV input.

ABSTRACT: To better understand the cortical circuitry underlying connectivity between large-scale neural networks, we develop a novel, data-driven approach to identify potential integration subregions. Between-network connectivity (BNC) associated with any anatomical region is the amount of connectivity between that point and all large-scale networks, as measured using simple and multiple correlations. It is straightforward to calculate and applicable to functional networks identified using independent components analysis. We calculated BNC for all fMRI voxels within the brain and compared the results to known regional cytoarchitectural patterns. Based on previous observations of the relationship between macroscopic connectivity and microscopic cytoarchitecture, we predicted that areas with high BNC

SUBMITTER: Wylie KP 

PROVIDER: S-EPMC4468026 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature