A Hierarchical Factor Model of Executive Functions in Adolescents: Evidence of Gene-Environment Interplay.

ABSTRACT: Executive functions (EF) are a complex set of neurodevelopmental, higher-ordered processes that are especially salient during adolescence. Disruptions to these processes are predictive of psychiatric problems in later adolescence and adulthood. The objectives of the current study were to characterize the latent structure of EF using bifactor analysis and to investigate the independent and interactive effects of genes and environments on EF during adolescence. Using a representative young adolescent sample, we tested the interaction of a polymorphism in the serotonin transporter gene (5-HTTLPR) and parental supervision for EF through hierarchical linear regression. To account for the possibility of a hierarchical factor structure for EF, a bifactor analysis was conducted on the eight subtes

SUBMITTER: Li JJ 

PROVIDER: S-EPMC4468042 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature