Factors affecting maternal participation in the genetic component of the National Birth Defects Prevention Study-United States, 1997-2007.

ABSTRACT:

Purpose

As epidemiological studies expand to examine gene-environment interaction effects, it is important to identify factors associated with participation in genetic studies. The National Birth Defects Prevention Study is a multisite case-control study designed to investigate environmental and genetic risk factors for major birth defects. The National Birth Defects Prevention Study includes maternal telephone interviews and mailed buccal cell self-collection kits. Because subjects can participate in the interview, independent of buccal cell collection, detailed analysis of factors associated with participation in buccal cell collection was possible.

Methods

Multivariable logistic regression models were used to identify the factors associated with participation in the genet

SUBMITTER: Glidewell J 

PROVIDER: S-EPMC4471475 | biostudies-literature | 2014 Apr

REPOSITORIES: biostudies-literature