Association between Dental Caries and Down Syndrome: A Systematic Review and Meta-Analysis.

ABSTRACT: Scientific evidence of susceptibility to dental caries in the population with Down Syndrome (DS) is limited and conflicting, making it difficult to establish firm conclusions. The aim of this systematic review and meta-analysis was to obtain scientific evidence of the possible association between dental caries and individuals with DS, compared to individuals without DS (control). An electronic search of five databases was performed, with no language or publication date restrictions. The studies were selected by two independent reviewers (Kappa = 0.83). The systematic review included 13 studies, while eight studies were included in the meta-analysis. The studies are presumably all at risk of bias given their observational character. Two of these evaluated the presence or absence of caries i

SUBMITTER: Deps TD 

PROVIDER: S-EPMC4472226 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature