Cold adaptation shapes the robustness of metabolic networks in Drosophila melanogaster.

ABSTRACT: When ectotherms are exposed to low temperatures, they enter a cold-induced coma (chill coma) that prevents resource acquisition, mating, oviposition, and escape from predation. There is substantial variation in time taken to recover from chill coma both within and among species, and this variation is correlated with habitat temperatures such that insects from cold environments recover more quickly. This suggests an adaptive response, but the mechanisms underlying variation in recovery times are unknown, making it difficult to decisively test adaptive hypotheses. We use replicated lines of Drosophila melanogaster selected in the laboratory for fast (hardy) or slow (susceptible) chill-coma recovery times to investigate modifications to metabolic profiles associated with cold adaptation. We m

SUBMITTER: Williams CM 

PROVIDER: S-EPMC4472466 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature