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Coproduction of KPC-2 and IMP-10 in Carbapenem-Resistant Serratia marcescens Isolates from an Outbreak in a Brazilian Teaching Hospital.

ABSTRACT: We describe an outbreak caused by KPC-2- and IMP-10-producing Serratia marcescens isolates in a Brazilian teaching hospital. Tigecycline was the only active antimicrobial agent tested. The blaIMP-10 gene was located in a new class 1 integron, named In990, carried by a nonconjugative plasmid, in contrast to blaKPC-2.

SUBMITTER: Silva KE 

PROVIDER: S-EPMC4473237 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature

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Coproduction of KPC-2 and IMP-10 in Carbapenem-Resistant Serratia marcescens Isolates from an Outbreak in a Brazilian Teaching Hospital.

Silva Kesia Esther KE   Cayô Rodrigo R   Carvalhaes Cecilia Godoy CG   Patussi Correia Sacchi Flávia F   Rodrigues-Costa Fernanda F   Ramos da Silva Ana Carolina AC   Croda Julio J   Gales Ana Cristina AC   Simionatto Simone S  

Journal of clinical microbiology 20150415 7

We describe an outbreak caused by KPC-2- and IMP-10-producing Serratia marcescens isolates in a Brazilian teaching hospital. Tigecycline was the only active antimicrobial agent tested. The blaIMP-10 gene was located in a new class 1 integron, named In990, carried by a nonconjugative plasmid, in contrast to blaKPC-2. ...[more]

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