XPD Lys⁷⁵¹Gln and Asp³¹²Asn polymorphisms and hepatocellular carcinoma susceptibility: A meta-analysis of 11 case-control studies in an Asian population.

ABSTRACT: This meta-analysis was performed to evaluate the association between xeroderma pigmentosum complementary group D (XPD) Lys⁷⁵¹Gln and Asp³¹²Asn polymorphisms and susceptibility to hepatocellular carcinoma (HCC). PubMed, Embase, Google Scholar and the Chinese National Knowledge Infrastructure and the Chinese Biomedicine databases were systematically searched to identify relevant studies published up to June 1, 2014. Statistical analyses were performed using Stata version 12.0 software. A total of 11 case-control studies, comprising 2,852 cases and 2,936 controls, were included. The results of the meta-analysis revealed that a significant association between the risk of HCC and variant genotypes of the XPD Lys⁷⁵¹Gln and Asp³¹²Asn polymorphisms was e

SUBMITTER: Yang QI 

PROVIDER: S-EPMC4473668 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature