Fabrication of Polymeric Coatings with Controlled Microtopographies Using an Electrospraying Technique.

ABSTRACT: Surface topography of medical implants provides an important biophysical cue on guiding cellular functions at the cell-implant interface. However, few techniques are available to produce polymeric coatings with controlled microtopographies onto surgical implants, especially onto implant devices of small dimension and with complex structures such as drug-eluting stents. Therefore, the main objective of this study was to develop a new strategy to fabricate polymeric coatings using an electrospraying technique based on the uniqueness of this technique in that it can be used to produce a mist of charged droplets with a precise control of their shape and dimension. We hypothesized that this technique would allow facile manipulation of coating morphology by controlling the shape and dimension of

SUBMITTER: Guo Q 

PROVIDER: S-EPMC4475032 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature