Usefulness of data from magnetic resonance imaging to improve prediction of dementia: population based cohort study.

ABSTRACT:

Objective

To determine whether the addition of data derived from magnetic resonance imaging (MRI) of the brain to a model incorporating conventional risk variables improves prediction of dementia over 10 years of follow-up.

Design

Population based cohort study of individuals aged ≥ 65.

Setting

The Dijon magnetic resonance imaging study cohort from the Three-City Study, France.

Participants

1721 people without dementia who underwent an MRI scan at baseline and with known dementia status over 10 years' follow-up.

Main outcome measure

Incident dementia (all cause and Alzheimer's disease).

Results

During 10 years of follow-up, there were 119 confirmed cases of dementia, 84 of which were Alzheimer's disease. The conventional risk model incorporated age

SUBMITTER: Stephan BC 

PROVIDER: S-EPMC4476487 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature