Estimation of biomarker distributions using laboratory data collected during routine delivery of medical care.

ABSTRACT:

Purpose

To examine the extent to which commonly ordered laboratory values obtained from large health care databases are representative of the distribution of laboratory values from the general population as reflected in the National Health and Nutrition Examination Survey.

Methods

Means of test values from commercial insurance laboratory data and National Health and Nutrition Examination Survey data were compared. Inverse probability of selection weighting was used to account for possible selection bias and to create comparability between the two data sources.

Results

The average values of most of the laboratory results from routine care were very close to their population means as estimated from NHANES. Tests that were more selectively ordered tended to differ. The i

SUBMITTER: Brookhart MA 

PROVIDER: S-EPMC4476533 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature