Oviductal Transcriptome Is Modified after Insemination during Spontaneous Ovulation in the Sow.

ABSTRACT: Gene Expression Microarray technology was used to compare oviduct transcriptome between inseminated and non-inseminated pigs during spontaneous oestrus. We used an in vivo model approaching the study from a physiological point of view in which no hormonal treatment (animals were in natural oestrus) and no artificial sperm selection (selection was performed within the female genital) were imposed. It is therefore emphasised that no surgical introduction of spermatozoa and no insemination at a site other than the physiological one were used. This approach revealed 17 genes that were two-fold or more up-regulated in oviducts exposed to spermatozoa and/or developing embryos and 9 genes that were two-fold or more down-regulated. Functional analysis of the genes revealed that the top canonical p

SUBMITTER: Lopez-Ubeda R 

PROVIDER: S-EPMC4476686 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature