Antidiabetic and cardiovascular drug utilisation in patients diagnosed with type 2 diabetes mellitus over the age of 80 years: a population-based cohort study.

ABSTRACT:

Background

there is a lack of evidence to inform treatment recommendations for very old people with type 2 diabetes mellitus (T2DM).

Objective

to evaluate trends in antidiabetic and cardiovascular drug utilisation for patients developing T2DM over 80 years of age.

Methods

a population-based cohort was sampled from the UK Clinical Practice Research Datalink between 1990 and 2013. Eligible patients were those with T2DM diagnosed after the age of 80 years and prescribed antidiabetic drugs.

Results

twelve thousand eight hundred and eighty-one patients, with 61% of females, were included. From 1990 to 2013, use of sulphonylureas declined from 94 to 29%, while metformin use increased from 22 to 86%. Prescribing of antihypertensive drugs increased substantially from 4

SUBMITTER: Hamada S 

PROVIDER: S-EPMC4476852 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature