Non-axial view of the varicella-zoster virus portal protein reveals conserved crown, wing and clip architecture.
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ABSTRACT:
SUBMITTER: Visalli RJ
PROVIDER: S-EPMC4477527 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Publications
Non-axial view of the varicella-zoster virus portal protein reveals conserved crown, wing and clip architecture.
Visalli Robert J RJ Howard Alexander J AJ
Intervirology 20140314 2
<h4>Background</h4>Herpesviridae encode a family of protein homologues that function as the 'port of entry' for insertion of the viral DNA into preformed capsids during encapsidation.<h4>Methods</h4>Transmission electron microscopy (TEM) of recombinant varicella-zoster virus pORF54 was performed.<h4>Results</h4>Results suggest that pORF54 forms higher-order structures with itself. Enriched fractions analyzed by TEM revealed non-axial oriented portals with defined central channels and distinguish ...[more]
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