Resistance Mechanisms of Anopheles stephensi (Diptera: Culicidae) to Temephos.

ABSTRACT:

Background

Anopheles stephensi is a sub-tropical species and has been considered as one of the most important vector of human malaria throughout the Middle East and South Asian region including the malarious areas of southern Iran. Current reports confirmed An. stephensi resistance to temephos in Oman and India. However, there is no comprehensive research on mechanisms of temephos resistance in An. stephensi in the literature. This study was designed in order to clarify the enzymatic and molecular mechanisms of temephos resistance in this species.

Methods

Profile activities of α- and ß-esterases, mixed function oxidase (MFO), glutathione-S-transferase (GST), insensitive acetylcholinesterase, and para-nitrophenyl acetate (PNPA)-esterase enzymes were tested for An. stephensi s

SUBMITTER: Soltani A 

PROVIDER: S-EPMC4478420 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature