Spatiotemporal dynamics of Puumala hantavirus associated with its rodent host, Myodes glareolus.

ABSTRACT: Many viruses significantly impact human and animal health. Understanding the population dynamics of these viruses and their hosts can provide important insights for epidemiology and virus evolution. Puumala virus (PUUV) is a European hantavirus that may cause regional outbreaks of hemorrhagic fever with renal syndrome in humans. Here, we analyzed the spatiotemporal dynamics of PUUV circulating in local populations of its rodent reservoir host, the bank vole (Myodes glareolus) during eight years. Phylogenetic and population genetic analyses of all three genome segments of PUUV showed strong geographical structuring at a very local scale. There was a high temporal turnover of virus strains in the local bank vole populations, but several virus strains persisted through multiple years. Phylody

SUBMITTER: Weber de Melo V 

PROVIDER: S-EPMC4479511 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature