Preoperative magnetic resonance imaging for detecting uni- and bilateral extraprostatic disease in patients with prostate cancer.

ABSTRACT:

Objective

The objective of the study was to evaluate the diagnostic accuracy of preoperative magnetic resonance imaging (MRI) for detecting uni- and bilateral extraprostatic disease (T3) in patients with prostate cancer (PCa).

Materials and methods

This prospective study included 199 patients with biopsy-proven PCa who underwent MRI prior to radical prostatectomy from December 2009 to July 2012. Extraprostatic extension and seminal vesicle invasion represented T3 disease, and was classified as uni- (right or left) or bilateral. MRI detection of T3 disease was assessed by descriptive statistics and odds ratio (OR). Whole-mount histopathology was used as the reference standard.

Results

The overall prevalence of pT3 was 105/199 (53 %), unilateral in 81/105 (77 %) and bil

SUBMITTER: Rud E 

PROVIDER: S-EPMC4480330 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature