Using Fourier transform IR spectroscopy to analyze biological materials.

ABSTRACT: IR spectroscopy is an excellent method for biological analyses. It enables the nonperturbative, label-free extraction of biochemical information and images toward diagnosis and the assessment of cell functionality. Although not strictly microscopy in the conventional sense, it allows the construction of images of tissue or cell architecture by the passing of spectral data through a variety of computational algorithms. Because such images are constructed from fingerprint spectra, the notion is that they can be an objective reflection of the underlying health status of the analyzed sample. One of the major difficulties in the field has been determining a consensus on spectral pre-processing and data analysis. This manuscript brings together as coauthors some of the leaders in this field to a

SUBMITTER: Baker MJ 

PROVIDER: S-EPMC4480339 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature