Management of acute variceal bleeding using hemostatic powder.

ABSTRACT:

Background and objectives

This study aimed to test the safety and efficacy of Hemospray® for emergency control of acute variceal bleeding (AVB) due to portal hypertension in cirrhotic patients.

Patients and methods

This single-arm, prospective trial, conducted at two hospitals in Belgium and Egypt, included patients admitted to the emergency room with hematemesis and/or melena and known or suspected liver cirrhosis. All patients received urgent hemodynamic stabilization, octreotide (50 mcg bolus then 25 mcg/hour for 24 hours) and intravenous ceftriaxone (1 g/hour). Endoscopy to confirm AVB and Hemospray® application (if indicated) was performed within six hours of admission. Patients were kept under observation for 24 hours and underwent second endoscopy and definitive thera

SUBMITTER: Ibrahim M 

PROVIDER: S-EPMC4480536 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature