Fish oil-derived n-3 PUFA therapy increases muscle mass and function in healthy older adults.

ABSTRACT:

Background

Age-associated declines in muscle mass and function are major risk factors for an impaired ability to carry out activities of daily living, falls, prolonged recovery time after hospitalization, and mortality in older adults. New strategies that can slow the age-related loss of muscle mass and function are needed to help older adults maintain adequate performance status to reduce these risks and maintain independence.

Objective

We evaluated the efficacy of fish oil-derived n-3 (ω-3) PUFA therapy to slow the age-associated loss of muscle mass and function.

Design

Sixty healthy 60-85-y-old men and women were randomly assigned to receive n-3 PUFA (n = 40) or corn oil (n = 20) therapy for 6 mo. Thigh muscle volume, handgrip strength, one-repetition maximum (1-RM

SUBMITTER: Smith GI 

PROVIDER: S-EPMC4480667 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature