Higher usual alcohol consumption was associated with a lower 41-y mortality risk from coronary artery disease in men independent of genetic and common environmental factors: the prospective NHLBI Twin Study.

ABSTRACT:

Background

Evidence that alcohol consumption is inversely associated with long-term coronary artery disease (CAD) mortality independent of genetic and early life environmental factors is lacking.

Objective

We evaluated whether alcohol consumption was prospectively associated with CAD mortality risk independent of familial factors.

Design

In total, 843 male twins (396 pairs and 51 unpaired twins) aged 42-55 y (mean: 48 y) without baseline CAD reported beer, wine, and spirits consumption at baseline (1969-1973) and were followed up to 2010 in the prospective National Heart, Lung, and Blood Institute Twin Study. Data on usual alcohol consumption over the past year were collected. Outcome was time to event, where the primary event was death from CAD and secondary events w

SUBMITTER: Dai J 

PROVIDER: S-EPMC4480668 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature