Nickel-catalyzed amination of aryl chlorides with ammonia or ammonium salts.

ABSTRACT: The nickel-catalyzed amination of aryl chlorides to form primary arylamines occurs with ammonia or ammonium sulfate and a well-defined single-component nickel(0) precatalyst containing a Josiphos ligand and an η(2)-bound benzonitrile ligand. This system also catalyzes the coupling of aryl chlorides with gaseous amines in the form of their hydrochloride salts.

SUBMITTER: Green RA 

PROVIDER: S-EPMC4480680 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature