Gamma Oscillations and Their Cross-frequency Coupling in the Primate Hippocampus during Sleep.

ABSTRACT:

Study objectives

The mechanism by which sleep consolidates memory is unclear. Based on the two-stage model of memory consolidation, different functions for slow wave sleep (SWS) and rapid eye movement (REM) sleep have been proposed; thus, state-dependent changes of neural oscillations in the hippocampus might clarify this fundamental question.

Methods

We recorded hippocampal local field potentials from freely behaving monkeys via telemetry and analyzed their nonstationary oscillations using Hilbert-Huang transform.

Results

By applying a recently developed empirical mode decomposition analysis, we found strong cross-frequency coupling between high-frequency and slow wave oscillations during SWS and a prominent increase of gamma band activity in short bursts during REM

SUBMITTER: Takeuchi S 

PROVIDER: S-EPMC4480998 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature