Urinary concentrations of bisphenol A and phthalate metabolites and weight change: a prospective investigation in US women.

ABSTRACT:

Objective

Both bisphenol A (BPA) and phthalates are known endocrine-disrupting chemicals for which there is widespread general population exposure. Human exposure occurs through dietary and non-dietary routes. Although animal studies have suggested a potential role of these chemicals in obesity, evidence from human studies is sparse and inconsistent, and prospective evidence is lacking. This study evaluated urinary concentrations of BPA and major phthalate metabolites in relation to prospective weight change.

Methods

The study population was from the controls in a prospective case-control study of type 2 diabetes in the Nurses' Health Study (NHS) and NHSII. A total of 977 participants provided first-morning-void urine samples in 1996-2002. Urinary concentrations of BPA and n

SUBMITTER: Song Y 

PROVIDER: S-EPMC4481130 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature