Blood Transfusions May Have Limited Effect on Muscle Oxygenation After Total Knee Arthroplasty.

ABSTRACT:

Background

Traditionally, blood transfusions in the perioperative setting are used to maintain adequate delivery of nutrients and oxygen to organs. However, the effect of blood administration on tissue oxygenation in the perioperative setting remains poorly understood.

Questions/purposes

The aim of this study was to determine changes in muscle tissue oxygenation saturation (SmO2) in response to perioperative blood transfusions.

Patients and methods

Patients undergoing total knee arthroplasty were enrolled. SmO2, continuous hemoglobin (SpHb), stroke volume (SV), cardiac index, and standard hemodynamic parameters including heart rate (HR), mean arterial blood pressure (MAP), and arterial oxygen saturation (SO2) were recorded. To assess fluid responsiveness, a passive le

SUBMITTER: Memtsoudis SG 

PROVIDER: S-EPMC4481255 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature