Carotid Intima Media Thickness, Atherosclerosis, and 5-Year Decline in Odor Identification: The Beaver Dam Offspring Study.

ABSTRACT:

Background

The purpose of this study was to determine if subclinical markers of atherosclerosis are associated with a decline in olfactory function.

Methods

The San Diego Odor Identification Test was administered to 2,302 participants (age 21-84 years) at the baseline (2005-2008) and 5-year follow-up (2010-2013) examinations of the Beaver Dam Offspring Study. A decline in odor identification was defined as a decrease in San Diego Odor Identification Test score of 2 or more (range 0-8) from Beaver Dam Offspring Study 1 to Beaver Dam Offspring Study 2. Carotid intima media thickness and plaque, blood pressure, pulse wave velocity, and body mass index were measured and other risk factor data were obtained by interview.

Results

Overall 3.2% of participants had a decline i

SUBMITTER: Schubert CR 

PROVIDER: S-EPMC4481687 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature