A Systematic Review of the Mortality from Untreated Leptospirosis.

ABSTRACT:

Background

Leptospirosis occurs worldwide, but the global incidence of human disease and its mortality are not well understood. Many patients are undiagnosed and untreated due to its non-specific symptoms and a lack of access to diagnostics. This study systematically reviews the literature to clarify the mortality from untreated leptospirosis. Results will help quantify the global burden of disease and guide health policies.

Methodology/principal findings

A comprehensive literature search was performed to identify untreated patient series. Included patients were symptomatic, but asymptomatic patients and those who had received antibiotics, dialysis or who were treated on Intensive Care Units were excluded. Included patients had a confirmed laboratory diagnosis by culture, PC

SUBMITTER: Taylor AJ 

PROVIDER: S-EPMC4482028 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature