Effect of brain structure and function on reward anticipation in children and adults with attention deficit hyperactivity disorder combined subtype.

ABSTRACT: Attention deficit hyperactivity disorder (ADHD) is associated with decreased ventral-striatal responsiveness during reward anticipation. However, previous research mostly focused on adults with heterogeneous ADHD subtype and divers drug treatment status while studies in children with ADHD are sparse. Moreover, it remains unclear to what degree ADHD is characterized by a delay of normal brain structure or function maturation. We therefore attempt to determine whether results from structural and functional magnetic resonance imaging (fMRI) are associated with childhood and adult ADHD combined subtype (ADHD-CT). This study used fMRI to compare VS structure and function of 30 participants with ADHD-CT (16 adults, 14 children) and 30 controls (20 adults, 10 children), using a monetary incentive

SUBMITTER: Kappel V 

PROVIDER: S-EPMC4483558 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature