The association of hospital prevention processes and patient risk factors with the risk of Clostridium difficile infection: a population-based cohort study.

ABSTRACT:

Background

Clostridium difficile is the most common cause of healthcare-acquired infection; the real-world impacts of some proposed C. difficile prevention processes are unknown.

Methods

We conducted a population-based retrospective cohort study of all patients admitted to acute care hospitals between April 2011 and March 2012 in Ontario, Canada. Hospital prevention practices were determined by survey of infection control programmes; responses were linked to patient-level risk factors and C. difficile outcomes in Ontario administrative databases. Multivariable generalised estimating equation (GEE) regression models were used to assess the impact of selected understudied hospital prevention processes on the patient-level risk of C. difficile infection, accounting for patient

SUBMITTER: Daneman N 

PROVIDER: S-EPMC4484271 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature