Correlates of self-reported dietary cruciferous vegetable intake and urinary isothiocyanate from two cohorts in China.

ABSTRACT:

Objective

To assess correlations between cruciferous vegetable intake and urinary isothiocyanate (ITC) level, in addition to glutathione S-transferase (GST) genotypes and other individual factors.

Design

The study included cohort participants whose urinary ITC levels had been previously ascertained. Urinary ITC was assessed using HPLC. Usual dietary intake of cruciferous vegetables was assessed using a validated FFQ and total dietary ITC intake was calculated. Recent cruciferous vegetable intake was determined. GST genotypes were assessed using duplex real-time quantitative PCR assays. Spearman correlations were calculated between the covariates and urinary ITC levels and linear regression analyses were used to calculate the mean urinary ITC excretion according to GST genoty

SUBMITTER: Vogtmann E 

PROVIDER: S-EPMC4485386 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature