ToxoMine: an integrated omics data warehouse for Toxoplasma gondii systems biology research.

ABSTRACT: Toxoplasma gondii (T. gondii) is an obligate intracellular parasite that must monitor for changes in the host environment and respond accordingly; however, it is still not fully known which genetic or epigenetic factors are involved in regulating virulence traits of T. gondii. There are on-going efforts to elucidate the mechanisms regulating the stage transition process via the application of high-throughput epigenomics, genomics and proteomics techniques. Given the range of experimental conditions and the typical yield from such high-throughput techniques, a new challenge arises: how to effectively collect, organize and disseminate the generated data for subsequent data analysis. Here, we describe toxoMine, which provides a powerful interface to support sophisticated integrative explorati

SUBMITTER: Rhee DB 

PROVIDER: S-EPMC4485433 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature