Estimating the lifetime risk of dementia in the Canadian elderly population using cross-sectional cohort survival data.

ABSTRACT: Dementia is one of the world's major public health challenges. The lifetime risk of dementia is the proportion of individuals who ever develop dementia during their lifetime. Despite its importance to epidemiologists and policy-makers, this measure does not seem to have been estimated in the Canadian population. Data from a birth cohort study of dementia are not available. Instead, we must rely on data from the Canadian Study of Heath and Aging, a large cross-sectional study of dementia with follow-up for survival. These data present challenges because they include substantial loss to follow-up and are not representatively drawn from the target population because of structural sampling biases. A first bias is imparted by the cross-sectional sampling scheme, while a second bias is a result

SUBMITTER: Carone M 

PROVIDER: S-EPMC4485460 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature