Spatial analysis of advanced-stage ovarian cancer mortality in California.

ABSTRACT:

Objective

We sought to determine the impact of geographic location on advanced-stage ovarian cancer mortality in relation to adherence to National Comprehensive Cancer Network (NCCN) treatment guidelines and hospital case volume.

Study design

This was a retrospective observational cohort study of patients diagnosed with stage IIIC/IV epithelial ovarian cancer (Jan. 1, 1996, through Dec. 31, 2006) identified from the California Cancer Registry. Generalized additive models were created to assess the effect of spatial distributions of geographic location, demographic characteristics, disease-related variables, adherence to NCCN guidelines, and hospital case volume, with simultaneous smoothing of geographic location and adjustment for confounding variables.

Results

A tota

SUBMITTER: Bristow RE 

PROVIDER: S-EPMC4485540 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature