"In situ" vaccination for systemic effects in follicular lymphoma.

ABSTRACT: Therapeutic vaccines for follicular lymphoma have had limited success. A novel in situ immunotherapeutic strategy combining 3 different treatment modalities induced regression of disseminated follicular lymphoma, which correlated with systemic antitumor T-cell immunity. These results should renew interest in the development of local combined radio- and immunotherapies to achieve abscopal effects.

SUBMITTER: Kolstad A 

PROVIDER: S-EPMC4485726 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature