Multicentre randomized controlled trial comparing ferric(III)carboxymaltose infusion with oral iron supplementation in the treatment of preoperative anaemia in colorectal cancer patients.

ABSTRACT:

Background

At least a third of patients with a colorectal carcinoma who are candidate for surgery, are anaemic preoperatively. Preoperative anaemia is associated with increased morbidity and mortality. In general practice, little attention is paid to these anaemic patients. Some will have oral iron prescribed others not. The waiting period prior to elective colorectal surgery could be used to optimize a patients' physiological status. The aim of this study is to determine the efficacy of preoperative intravenous iron supplementation in comparison with the standard preoperative oral supplementation in anaemic patients with colorectal cancer.

Methods/design

In this multicentre randomized controlled trial, patients with an M0-staged colorectal carcinoma who are scheduled for cu

SUBMITTER: Borstlap WAA 

PROVIDER: S-EPMC4485873 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature