Pattern-Based Detection of Anion Pollutants in Water with DNA Polyfluorophores.

ABSTRACT: Many existing irrigation, industrial and chemical storage sites are currently introducing hazardous anions into groundwater, making the monitoring of such sites a high priority. Detecting and quantifying anions in water samples typically requires complex instrumentation, adding cost and delaying analysis. Here we address these challenges by development of an optical molecular method to detect and discriminate a broad range of anionic contaminants with DNA-based fluorescent sensors. A library of 1296 tetrameric-length oligodeoxyfluorosides (ODFs) composed of metal ligand and fluorescence modulating monomers was constructed with a DNA synthesizer on PEG-polystyrene microbeads. These oligomers on beads were incubated with Y^III or Zn^II ions to provide affinity and respons

SUBMITTER: Kwon H 

PROVIDER: S-EPMC4486361 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature