FlyNet: a versatile network prioritization server for the Drosophila community.

ABSTRACT: Drosophila melanogaster (fruit fly) has been a popular model organism in animal genetics due to the high accessibility of reverse-genetics tools. In addition, the close relationship between the Drosophila and human genomes rationalizes the use of Drosophila as an invertebrate model for human neurobiology and disease research. A platform technology for predicting candidate genes or functions would further enhance the usefulness of this long-established model organism for gene-to-phenotype mapping. Recently, the power of network prioritization for gene-to-phenotype mapping has been demonstrated in many organisms. Here we present a network prioritization server dedicated to Drosophila that covers ∼95% of the coding genome. This server, dubbed FlyNet, has several distinctive features, includin

SUBMITTER: Shin J 

PROVIDER: S-EPMC4489278 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature