MyProteinNet: build up-to-date protein interaction networks for organisms, tissues and user-defined contexts.

ABSTRACT: The identification of the molecular pathways active in specific contexts, such as disease states or drug responses, often requires an extensive view of the potential interactions between a subset of proteins. This view is not easily obtained: it requires the integration of context-specific protein list or expression data with up-to-date data of protein interactions that are typically spread across multiple databases. The MyProteinNet web server allows users to easily create such context-sensitive protein interaction networks. Users can automatically gather and consolidate data from up to 11 different databases to create a generic protein interaction network (interactome). They can score the interactions based on reliability and filter them by user-defined contexts including molecular expre

SUBMITTER: Basha O 

PROVIDER: S-EPMC4489290 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature