MiRiadne: a web tool for consistent integration of miRNA nomenclature.

ABSTRACT: The miRBase is the official miRNA repository which keeps the annotation updated on newly discovered miRNAs: it is also used as a reference for the design of miRNA profiling platforms. Nomenclature ambiguities generated by loosely updated platforms and design errors lead to incompatibilities among platforms, even from the same vendor. Published miRNA lists are thus generated with different profiling platforms that refer to diverse and not updated annotations. This greatly compromises searches, comparisons and analyses that rely on miRNA names only without taking into account the mature sequences, which is particularly critic when such analyses are carried over automatically. In this paper we introduce miRiadne, a web tool to harmonize miRNA nomenclature, which takes into account the origina

SUBMITTER: Bonnal RJ 

PROVIDER: S-EPMC4489305 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature