(PS)2: protein structure prediction server version 3.0.

ABSTRACT: Protein complexes are involved in many biological processes. Examining coupling between subunits of a complex would be useful to understand the molecular basis of protein function. Here, our updated (PS)(2) web server predicts the three-dimensional structures of protein complexes based on comparative modeling; furthermore, this server examines the coupling between subunits of the predicted complex by combining structural and evolutionary considerations. The predicted complex structure could be indicated and visualized by Java-based 3D graphics viewers and the structural and evolutionary profiles are shown and compared chain-by-chain. For each subunit, considerations with or without the packing contribution of other subunits cause the differences in similarities between structural and evolu

SUBMITTER: Huang TT 

PROVIDER: S-EPMC4489310 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature