GalaxyPepDock: a protein-peptide docking tool based on interaction similarity and energy optimization.

ABSTRACT: Protein-peptide interactions are involved in a wide range of biological processes and are attractive targets for therapeutic purposes because of their small interfaces. Therefore, effective protein-peptide docking techniques can provide the basis for potential therapeutic applications by enabling an atomic-level understanding of protein interactions. With the increasing number of protein-peptide structures deposited in the protein data bank, the prediction accuracy of protein-peptide docking can be enhanced by utilizing the information provided by the database. The GalaxyPepDock web server, which is freely accessible at http://galaxy.seoklab.org/pepdock, performs similarity-based docking by finding templates from the database of experimentally determined structures and building models usin

SUBMITTER: Lee H 

PROVIDER: S-EPMC4489314 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature