Transmission of Mycobacterium tuberculosis in China: a population-based molecular epidemiologic study.

ABSTRACT:

Background

Understanding the transmission of Mycobacterium tuberculosis is essential for the development of efficient tuberculosis control strategies. China has the second-largest tuberculosis burden in the world. Recent transmission and infection with M. tuberculosis, particularly drug-resistant strains, may account for many new tuberculosis cases.

Methods

We performed a population-based molecular epidemiologic study of pulmonary tuberculosis in China during 1 July 2009 to 30 June 2012. We defined clusters as cases with identical variable number tandem repeat genotype patterns and identified the risk factors associated with clustering, by logistic regression. Relative transmission rates were estimated by the sputum smear status and drug susceptibility status of tuberculosis

SUBMITTER: Yang C 

PROVIDER: S-EPMC4490233 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature