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Effect of oral taurine on morbidity and mortality in elderly hip fracture patients: a randomized trial.


ABSTRACT: Hip fracture patients represent a large part of the elderly surgical population and face severe postoperative morbidity and excessive mortality compared to adult surgical hip fracture patients. Low antioxidant status and taurine deficiency is common in the elderly, and may negatively affect postoperative outcome. We hypothesized that taurine, an antioxidant, could improve clinical outcome in the elderly hip fracture patient. A double blind randomized, placebo controlled, clinical trial was conducted on elderly hip fracture patients. Supplementation started after admission and before surgery up to the sixth postoperative day. Markers of oxidative status were measured during hospitalization, and postoperative outcome was monitored for one year after surgery. Taurine supplementation did not i

SUBMITTER: Van Stijn MF 

PROVIDER: S-EPMC4490444 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature