Positional RNA-Seq identifies candidate genes for phenotypic engineering of sexual traits.

ABSTRACT:

Introduction

RNA interference (RNAi) of trait-specific genes permits the manipulation of specific phenotypic traits ("phenotypic engineering") and thus represents a powerful tool to test trait function in evolutionary studies. The identification of suitable candidate genes, however, often relies on existing functional gene annotation, which is usually limited in emerging model organisms, especially when they are only distantly related to traditional genetic model organisms. A case in point is the free-living flatworm Macrostomum lignano (Lophotrochozoa: Platyhelminthes: Rhabditophora), an increasingly powerful model organism for evolutionary studies of sex in simultaneous hermaphrodites. To overcome the limitation of sparse functional annotation, we have performed a positional RNA-

SUBMITTER: Arbore R 

PROVIDER: S-EPMC4490696 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature