Associations of Coffee Drinking with Systemic Immune and Inflammatory Markers.

ABSTRACT:

Background

Coffee drinking has been inversely associated with mortality as well as cancers of the endometrium, colon, skin, prostate, and liver. Improved insulin sensitivity and reduced inflammation are among the hypothesized mechanisms by which coffee drinking may affect cancer risk; however, associations between coffee drinking and systemic levels of immune and inflammatory markers have not been well characterized.

Methods

We used Luminex bead-based assays to measure serum levels of 77 immune and inflammatory markers in 1,728 older non-Hispanic Whites. Usual coffee intake was self-reported using a food frequency questionnaire. We used weighted multivariable logistic regression models to examine associations between coffee and dichotomized marker levels. We conducted statis

SUBMITTER: Loftfield E 

PROVIDER: S-EPMC4490956 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature