Identification of IL13 C1923T as a Single Nucleotide Polymorphism for Asthma in Children from Mauritius.

ABSTRACT: Background: Research increasingly suggests that asthma is a familial and hereditary disorder and that genetic and environmental factors play a key role in its pathogenesis. Objective: The aim of this study was to investigate the associations between 10 single nucleotide polymorphism (SNP) loci in the development of asthma in children from the Mauritian population. Methods: The study population consisted of 193 children with asthma and 189 healthy controls from the Mauritian population. Asthma was diagnosed in accordance with the American Thoracic Society criteria. TaqMan real-time quantitative polymerase chain reaction was used to detect the genotypes of the SNP loci. Results: No statistically significant differences (p>0.05) w

SUBMITTER: Ramphul K 

PROVIDER: S-EPMC4491167 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature