Association of Dietary Vitamin D and Calcium With Genetic Polymorphisms in Colorectal Neoplasia.

ABSTRACT: The incidence trends of colorectal cancer have varied over time, and there is wide geographical variation across the world. Regarding colorectal cancer, diverse modifiable environmental or intrinsic risk factors have been investigated. This review summarizes the effects of both dietary intake of vitamin D and calcium in particular and diet-associated genetic factors on colorectal cancer risk. We searched the electronic database PubMed for articles published between January 2000 and March 2015. We reviewed case-control studies that included dietary factors, genetic polymorphisms, and gene-diet interactions in association with colorectal cancer risk. Overall, 21 studies were selected as eligible studies. These studies demonstrated that dietary consumption of vitamin D and calcium may decreas

SUBMITTER: Park Y 

PROVIDER: S-EPMC4492365 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature