Genome Scan for Selection in Structured Layer Chicken Populations Exploiting Linkage Disequilibrium Information.

ABSTRACT: An increasing interest is being placed in the detection of genes, or genomic regions, that have been targeted by selection because identifying signatures of selection can lead to a better understanding of genotype-phenotype relationships. A common strategy for the detection of selection signatures is to compare samples from distinct populations and to search for genomic regions with outstanding genetic differentiation. The aim of this study was to detect selective signatures in layer chicken populations using a recently proposed approach, hapFLK, which exploits linkage disequilibrium information while accounting appropriately for the hierarchical structure of populations. We performed the analysis on 70 individuals from three commercial layer breeds (White Leghorn, White Rock and Rhode Isl

SUBMITTER: Gholami M 

PROVIDER: S-EPMC4494984 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature