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Explaining the Decrease of In-Hospital Mortality from Ischemic Stroke.


ABSTRACT:

Background

Mortality from ischemic stroke has declined over time. However, little is known about the reasons for the decreased mortality. We therefore aimed to evaluate trends in in-hospital mortality and to identify factors associated with these trends.

Methods

This study was based on a prospective database of 26 hospitals of the Stroke Register of Northwestern Germany, which included 73,614 patients admitted between 2000 and 2011. Time trends in observed (crude) and risk-adjusted in-hospital mortality were assessed. Independent factors associated with death after stroke were evaluated using multivariable logistic regression analysis.

Results

The observed in-hospital mortality decreased from 6.6% in 2000 to 4.6% in 2008 (P < 0.001 for trend) and then remained fairly

SUBMITTER: Minnerup J 

PROVIDER: S-EPMC4496086 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature