Change of Brain Functional Connectivity in Patients With Spinal Cord Injury: Graph Theory Based Approach.

ABSTRACT:

Objective

To investigate the global functional reorganization of the brain following spinal cord injury with graph theory based approach by creating whole brain functional connectivity networks from resting state-functional magnetic resonance imaging (rs-fMRI), characterizing the reorganization of these networks using graph theoretical metrics and to compare these metrics between patients with spinal cord injury (SCI) and age-matched controls.

Methods

Twenty patients with incomplete cervical SCI (14 males, 6 females; age, 55±14.1 years) and 20 healthy subjects (10 males, 10 females; age, 52.9±13.6 years) participated in this study. To analyze the characteristics of the whole brain network constructed with functional connectivity using rs-fMRI, graph theoretical measures were

SUBMITTER: Min YS 

PROVIDER: S-EPMC4496508 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature