Within-breath respiratory impedance and airway obstruction in patients with chronic obstructive pulmonary disease.

ABSTRACT:

Objective

Recent work has suggested that within-breath respiratory impedance measurements performed using the forced oscillation technique may help to noninvasively evaluate respiratory mechanics. We investigated the influence of airway obstruction on the within-breath forced oscillation technique in smokers and chronic obstructive pulmonary disease patients and evaluated the contribution of this analysis to the diagnosis of chronic obstructive pulmonary disease.

Methods

Twenty healthy individuals and 20 smokers were assessed. The study also included 74 patients with stable chronic obstructive pulmonary disease. We evaluated the mean respiratory impedance (Zm) as well as values for the inspiration (Zi) and expiration cycles (Ze) at the beginning of inspiration (Zbi) and expi

SUBMITTER: Silva KK 

PROVIDER: S-EPMC4496751 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature